Heartseed Inc. En Route To Clinical Trials Of Functional Cardiomyocytes

Top 10 Japanese Startups - 2021

Of the many factors, the one that has always steered Japan ahead of the competition curve is innovation. The capability of Japanese firms to embrace and develop new technologies enables them to bring out-of-the-box solutions to the table. A key role in this is being played by Japanese startups wherein fresh talents are always on the lookout for unprecedented approaches. Whether it is bringing our lucrative opportunities in the healthcare paradigm by revamping traditional medical processes and positioning technologies as a core revenue source or revolutionizing smart vehicle technology, Japanese startups are taking the technological landscape by storm. In fact, the innovation of miniature endoscopes exemplifies how Japanese companies are applying cutting-edge expertise to open doors for better healthcare opportunities. To that end, Japanese startups are also paving way for AI-based robots to increase automation of production lines and reduce the dependency on manual labor. IoH or the Internet of Humans that essentially combines AI and IoT is fast gaining popularity among Japanese enterprises to convert handwritten documents into effective digital processes.

Keeping in mind such drastic transitions, we have compiled this issue of Startup City in order to assist organizations in the task of finding accomplished solution providers to help them find eminent Japanese Startups. In this edition, we have listed Top 10 Japanese Startups–2021 to highlight the enterprises that can escalate the chances of your growth. Equipped with innovative technological capabilities, these enlisted startups are transforming variegated domains at the cloverleaf of various disruptive technologies. To help leaders navigate through the list of Japanese startups, our panel comprising CEOs, CIOs, VCs, industry analysts, and the editorial board of StartupCity has narrowed down the top firms in this landscape that exhibit competence in delivering robust solutions and innovations. Besides, the magazine comprises insights from subject-matter experts, CIOs, and CXOs in the startup realm on the latest industry trends, best practices, recent innovations, and highlights their expertise. We hope this issue of StartupCity helps you build the partnership you and your organization need to foster an environment driven by robust and efficient technology. We present to you StartupCity’s, “Top 10 Japanese Startups  Companies – 2021.

Top Japanese Startups

donut robotics offers advanced communication robots and a smart mask that focus on solving social problems and change the way people communicate in a post-COVID-19 world. The company has aimed to solve social problems across hospitals, elderly facilities, airports, and commercial facilities with small, mobile communication robots. With the COVID-19 pandemic came the limitless demand for face masks as governments and healthcare organizations globally made it mandatory to wear one. donut robotics rose to the occasion by innovating C-Face, a smart mask that acts as the high-tech upgrade of any face mask available in the market. In today’s era of social distancing, Ono and his team at donut robotics have emerged as the champion of safe communication


A Japan-based startup renowned for its high-precision 3D map (HD map) globally


Developing innovative cell therapies to treat heart failure and bringing ‘remuscularization’ – the next-gen regenerative medicine into the clinical stage


LEVIAS aims to bring innovation with the latest technology in the fintech sector. The company consists of a team of experts of programming, cryptography, blockchain, artificial intelligence etc. With its expertise, LEVIAS provides clients various digital technologies such as blockchain, STO platform, decentralized exchange, cryptocurrency issuance, payment system etc. The company’s mission is to cooperate with many partners beyond industry barriers, to develop innovation with the development of new technologies and services


MiCAN Technologies Inc. was founded in 2016, to contribute to the health of people everywhere, by providing blood cells for research using regenerative medicine technology. Today, MiCAN Technologies Inc. has developed three products: cells for young red blood cells for malaria research, immature dendritic cells for virus research, and immature dendritic cells modified for new coronavirus research. All blood cell products are young and immature cells, and the production technologies around it have been developed at universities and applied to commercialization. The company has been able to provide such specialized cells in large quantities and in a consistent manner


WOVN Technologies helps companies connect with their global audience easily through its Internet localization solution. The company has cracked the code of breaking the language barrier on the Internet with its multilingual localization. The company’s solution, WOVN.io, makes web and app content accessible to people across the globe in their native language. This paves the way for businesses to build and refine a successful overseas strategy. As a SaaS solution, WOVN.io can be implemented in an existing website easily. No unnecessary costs or additional human resources are required for system development and multilingual site operation


Zeals’ vision looks toward the “Omotenashi” Revolution. Omotenashi is the Japanese word for hospitality - a unique part of Japanese culture that Zeals, as a Japanese startup, wants to leverage to revolutionize the modern era across the world. The motivation for this revolution stems from the future society that the company is working toward - a "Will" society where communication tech is going to empower people to achieve their dreams and ambitions, and where technology is not just a tool that people will utilize, but a partner in their growth


atama plus

atama plus

Atama plus is an edtech startup company that utilizes AI for middle and high school students. The company’s product ‘atama +’ is a AI-based learning system to analyze data, such as learning history, proficiency level, and concentration level, and provide personal lessons to students. Currently, Atama plus offers services for cram schools and preparatory schools in nationwide. With the mission to improve society through education, the company aims to forge a new way of education that combines the strengths of both AI and people



Established in 2013, SmartDrive focuses on supporting the evolution of mobility. With this mission, the company is creating new services related to the movement in the IoT era by utilizing big data collected and analyzed through various sensor devices related to the movement. SmartDrive and has developed a platform that leads to openness regardless of manufacturer or affiliate, and the evolution of mobile. The compan’s services include safety and vehicle management, driver support, and monitoring services

Tier IV

Tier IV

Tier IV, a deep-tech startup based in Japan, is dedicated to sharing technology for safe intelligent vehicles that will benefit all of society by enabling as many individuals and organizations as possible to overcome the barriers of time and space to collectively bring autonomous vehicles into reality. Founded in December 2015, Tier IV has led the development of Autoware, the world's first open-source software for autonomous driving, and applied Autoware in applications of last-mile driverless mobility and logistics